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Gut 34: S59-60 (1993)[93300373]
Detection of HCV-RNA in saliva of patients with chronic
hepatitis C
P. Couzigou, L. Richard, F. Dumas, L. Schouler & H.
Fleury
Hepatogastroenterology Department, Centre Hospitalier Universitaire
de Bordeaux, Pessac, France.
Previous studies have provided conflicting results on the
presence of hepatitis C virus-RNA in saliva. In this study, 23
(62%) of 37 patients tested positive for hepatitis C virus-RNA in
saliva, using polymerase chain reaction analysis. A slightly
greater proportion had a sporadic rather than a parenteral origin
of chronic hepatitis C. These results provide a biological basis
for saliva as a possible source of hepatitis C virus (HCV)
infection, but do not necessarily imply transmission by this
route.
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