Total Protein test Protein, total (TP), plasma or serum
Normal Range: 6-8 g/dL
SI Range: 60-80 g/L
Blood tube color: Marbled
Specfics of collection: Avoid prolonged venous stasis during
The plasma protein concentration is determined by the nutritional
state, hepatic function, renal function, and various disease states
and hydration. The plasma protein concentration determines
colloidal osmotic pressure.
Increased in: Polyclonal or monoclonal gammopathies, marked
dehydration. Drugs: anabolic steroids, androgens, corticosteroids,
Decreased in: Protein-losing gastroenteropathies, acute burns,
nephrotic syndrome, severe dietary protein deficiency, chronic
liver disease, malabsorption syndrome, agammaglobulinemia.
The serum total protein consists primarily of albumin and globulin.
Hypoproteinemia usually means hypoalbuminemia, since albumin is the
major serum protein. Globulin is calculated as total protein minus
albumin. Source: Nicoll D, S. J. McPhee, T. M. Chou, W. M.
Detmer. Pocket Guide to Diagnostic Tests. Appleton & Lange,
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