Hepatitis Associated Vasculitic Multiple Mononeuropathy
History and clinical findings:
A 56-year-old woman with hepatitis C had symptoms of a
polyneuropathy with asymmetrical distal pareses and painful sensory
disturbances in the limbs.
In addition to positive serology for hepatitis C cryoglobulins were
demonstrated and complement C4 was reduced. Biopsy of the sural
nerve showed a vasculitic neuropathy.
Treatment and course:
The multiple neuropathy (cryoglobulinaemic neuropathy), associated
with hepatitis C, was treated with corticosteroids (starting with
60 mg/d prednisolone) and the neurological abnormalities regressed
Vasculitis associated with hepatitis C should be included in the
differential diagnosis of peripheral neuropathy.
Author: HECKMANN JG, UNIV ERLANGEN
NURNBERG, NEUROL KLIN, SHWABACHANLAGE 6 D-91054 ERLANGEN, GERMANY
Source: DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 1997
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