|
Home
What is
Hepatitis
How is it
Transmitted
Long Term
Prognosis
Complications of
HCV
Liver
Biopsy
Treatment Info
(Interferon, Herbal, etc)
Lab Tests (PCR,
Genotype,etc.)
Nutrition
& Alternative Info
Patient
Information (Support Groups, Doctor Listing,
etc)
Related
Webpages
Transplant
Info
Site
Search
HCV
Webrings
My
guestbookbook
Site
Awards
FAQ &
Disclaimers
|
Interferon induced sudden hearing loss
Abstract:
With the increasing long-term use of interferon (IFN), several new
adverse effects have been recognized. Very little attention,
however, has been paid to auditory acuity. We encountered 3 cases
of sudden hearing loss associated with IFN. We then conducted a
prospective study to assess the auditory function of 73 patients
receiving IFN.
Auditory disability (tinnitus and/or hearing loss) occurred in
32 patients (43.8%) during IFN therapy, among which audiometry
documented sensorineural hearing loss in 27 cases (36.9%); 17
(48.6%) of the 35 patients receiving IFN-beta had auditory
disability, including hearing loss in 13 cases (37.1%), and 15
(39.5%) of 38 patients receiving IFN-alpha suffered from auditory
disability. There was not much difference between the influences of
IFN-alpha and-beta. Auditory disability frequently developed in the
later stages of treatment, and most patients recovered 7-14 days
after the discontinuation of IFN. The results demonstrate that
sudden hearing loss can occur as a side effect of treatment with
IFN. This may reveal the association between autoimmunity and
sudden hearing loss.
Author: Kanda Y; Shigeno K; Matsuo H; Yano M; Yamada N;
Kumagami H
Address Department of Otolaryngology, Nagasaki University School of
Medicine, Japan.
Source: Audiology, 34: 2, 1995 Mar-Apr, 98-102
Home | What is HCV | Transmission |
Future |
Complications |
Biopsy |
Treatment
| Lab |
Nutrition |
Patient |
Links | Transplant |
Webrings |
guestbookbook |
Awards |
FAQ
|
|